发明公开
- 专利标题： ASSAYS FOR IDENTIFYING COMPOUNDS THAT MODULATE BITTER TASTE
- 专利标题（中）： 用于鉴定化合物，可用于苦味的调制
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申请号： EP14787491.1申请日： 2014-04-23
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公开(公告)号： EP2989464A1公开(公告)日： 2016-03-02
- 发明人: RADHAKRISHNA, Harish , JENKINS, Maya , ANOBILE, Jonathan
- 申请人： Chromocell Corporation
- 申请人地址： 685 U.S. Highway One North Brunswick, NJ 08902 US
- 专利权人： Chromocell Corporation
- 当前专利权人： Chromocell Corporation
- 当前专利权人地址： 685 U.S. Highway One North Brunswick, NJ 08902 US
- 代理机构： Hally, Anna-Louise
- 优先权： US201361815592P 20130424
- 国际公布： WO2014176336 20141030
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; C12N5/22
摘要：
The present invention is based on applicants' discovery, disclosed herein, of agonists for the TAS2R receptors TAS2R1, TAS2R4, TAS2R9, TAS2R13, TAS2R14, TAS2R16, TAS2R38, TAS2R39, TAS2R44, TAS2R46, and TAS2R60. The assignment of agonists to these receptors makes assays for identifying compounds that modulate bitter taste possible. For example, the present invention provides methods of identifying compounds that inhibit the bitter taste due to these agonists. The present invention also provides methods of identifying compounds that selectively inhibit the bitter taste due to these agonists. The present invention further provides methods of identifying compounds that mimic the bitter taste due these agonists. The present invention also provides methods of identifying compounds that enhance the bitter taste due to these agonists.
公开/授权文献
- EP2989464B1 ASSAYS FOR IDENTIFYING COMPOUNDS THAT MODULATE BITTER TASTE 公开/授权日：2018-12-26
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