发明公开
EP2990062A1 POLYPEPTIDE HYDROGEL AND METHOD FOR PRODUCING SAME
审中-公开
多米尼加共和国维多利亚州ZER HERSTELLUNG DAVON
- 专利标题： POLYPEPTIDE HYDROGEL AND METHOD FOR PRODUCING SAME
- 专利标题（中）： 多米尼加共和国维多利亚州ZER HERSTELLUNG DAVON
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申请号： EP14788691.5申请日： 2014-04-18
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公开(公告)号： EP2990062A1公开(公告)日： 2016-03-02
- 发明人: OSAWA, Toshiaki , MORITA, Keisuke
- 申请人： Spiber Inc.
- 申请人地址： 234-1, Aza Mizukami Kakuganji Tsuruoka-shi Yamagata 997-0052 JP
- 专利权人： Spiber Inc.
- 当前专利权人： Spiber Inc.
- 当前专利权人地址： 234-1, Aza Mizukami Kakuganji Tsuruoka-shi Yamagata 997-0052 JP
- 代理机构： Jones, Elizabeth Louise
- 优先权： JP2013092847 20130425
- 国际公布： WO2014175177 20141030
- 主分类号： A61L27/00
- IPC分类号： A61L27/00 ; C07K14/435 ; C12N15/09
摘要：
A polypeptide hydrogel of the present invention is a hydrogel of a polypeptide derived from spider silk proteins, and has a moisture content of 85.0 to 99.9 mass% based on 100 mass% of the polypeptide hydrogel. A method for producing the hydrogel includes: a solution production step in which a polypeptide derived from spider silk proteins is dissolved in at least one dissolving solvent selected from the group consisting of (A) dimethyl sulfoxide; (B) dimethyl sulfoxide with an inorganic salt; and (C) N, N-dimethylformamide with an inorganic salt, so as to obtain a solution of the polypeptide; and a substitution step in which the solution produced in the solution production step is substituted with a water-soluble solvent. Thus, the present invention provides a polypeptide hydrogel having excellent water retentivity and a polypeptide hydrogel suitable for application to a living body.
公开/授权文献
- EP2990062B1 POLYPEPTIDE HYDROGEL AND METHOD FOR PRODUCING SAME 公开/授权日：2021-11-10
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