Invention Publication
EP2995948A1 Methods and compounds useful in hematopoietic stem cell medicine
审中-公开
Verfahren und VerbindungenfürhämatopoetischeStammzellenmedizin
- Patent Title: Methods and compounds useful in hematopoietic stem cell medicine
- Patent Title (中): Verfahren und VerbindungenfürhämatopoetischeStammzellenmedizin
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Application No.: EP14184110.6Application Date: 2014-09-09
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Publication No.: EP2995948A1Publication Date: 2016-03-16
- Inventor: Vannini, Nicola , Lutolf, Matthias , Auwerx, Johan , Naveiras, Olaia , Girotra, Mukul
- Applicant: Ecole Polytechnique Federale de Lausanne (EPFL)
- Applicant Address: EPFL-TTO EPFL Innovation Park J 1015 Lausanne CH
- Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)
- Current Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)
- Current Assignee Address: EPFL-TTO EPFL Innovation Park J 1015 Lausanne CH
- Agency: reuteler & cie SA
- Main IPC: G01N33/50
- IPC: G01N33/50 ; C12N5/00 ; A61K31/06 ; A61K31/277 ; A61K31/405 ; A61K31/455 ; A61K31/496
Abstract:
The present invention relates to a specific marker for stem cells having long-term multi-lineage blood reconstitution capability and uses thereof for the preparation of cell composition in view of hematopoietic stem cell medicine and in particular regenerative therapies and bone marrow transplantation. Further, the invention relates to methods and compositions useful in the prevention and/or treatment of decreased blood cell levels and the associated risk of infection.
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