发明公开
EP2999715A2 NOVEL ANTIBODY USEFUL IN NEUROLOGICAL OR NEURODEGENERATIVE DISORDERS
审中-公开
新型抗体神经或神经退行性疾病
- 专利标题: NOVEL ANTIBODY USEFUL IN NEUROLOGICAL OR NEURODEGENERATIVE DISORDERS
- 专利标题(中): 新型抗体神经或神经退行性疾病
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申请号: EP14731163.3申请日: 2014-05-21
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公开(公告)号: EP2999715A2公开(公告)日: 2016-03-30
- 发明人: DOCAGNE, Fabian , MACREZ, Richard , VIVIEN, Denis , PETERSEN, Karl-Uwe
- 申请人: PAION Deutschland GmbH , Inserm
- 申请人地址: Martinstrasse 10-12 52062 Aachen DE
- 专利权人: PAION Deutschland GmbH,Inserm
- 当前专利权人: PAION Deutschland GmbH,Inserm
- 当前专利权人地址: Martinstrasse 10-12 52062 Aachen DE
- 代理机构: Cabinet Plasseraud
- 优先权: EP13002641 20130521; EP13002850 20130603
- 国际公布: WO2014187879 20141127
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61P9/10 ; A61P25/00
摘要:
The present invention relates to an anti-NMDA antibody or fragment or derivative thereof which is effective in inhibiting the deleterious effects of tissue-type plasminogen activator (t-PA) mediated by N-methyl-D-aspartate (NMDA) receptors and to medical uses, in particular for the treatment of neurological or neurodegenerative disorders, e.g. multiple sclerosis.
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