Methods of operating a wind turbine comprising a rotor with a plurality of blades, and one or more pitch mechanisms for rotating the blades around their rotational axes, a generator, and a system for varying a torque of the generator, and wherein each of the blades comprises one or more local aerodynamic actuators. The method comprises a sub-nominal zone of operation for wind speeds below a nominal wind speed and a supra-nominal zone of operation for wind speeds at or above the nominal wind speed. The sub-nominal zone of operation comprises a first operational range, a second operational range, and a third operational range. The method further comprises actuating the local aerodynamic actuators in the third operational range to increase the lift of the blade, and/or actuating the local aerodynamic actuators in the first operational range, to decrease the lift of the blade.