发明公开
EP3021852A4 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF
审中-公开
NEUROAKTIVE STEROIDE，ZUSAMMENSETZUNGEN DAMIT UND VERWENDUNGEN DAVON
- 专利标题： NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF
- 专利标题（中）： NEUROAKTIVE STEROIDE，ZUSAMMENSETZUNGEN DAMIT UND VERWENDUNGEN DAVON
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申请号： EP14826212申请日： 2014-07-18
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公开(公告)号： EP3021852A4公开(公告)日： 2017-03-22
- 发明人: MARTINEZ BOTELLA GABRIEL , HARRISON BOYD L , ROBICHAUD ALBERT JEAN , SALITURO FRANCESCO GERALD
- 申请人： SAGE THERAPEUTICS INC
- 专利权人： SAGE THERAPEUTICS INC
- 当前专利权人： SAGE THERAPEUTICS INC
- 优先权： US201361856592 2013-07-19
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; A61P25/00 ; C07J3/00
摘要：
Described herein are neuroactive steroids of the Formula (I): (Formula (I)) or a pharmaceutically acceptable salt thereof; wherein R1a and R1b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.
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