发明公开
- 专利标题： HETERO-CONDENSED RING COMPOUND
- 专利标题（中）： HETEROKONDENSIERTE RINGVERBINDUNG
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申请号： EP14829168.5申请日： 2014-07-18
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公开(公告)号： EP3026054A1公开(公告)日： 2016-06-01
- 发明人: TANAKA, Keigo , FUKUYAMA, Takashi , MURAI, Norio , ITANO, Wataru , HIROTA, Shinsuke , IIDA, Daisuke , AZUMA, Hiroshi
- 申请人： Eisai R&D Management Co., Ltd.
- 申请人地址： 4-6-10 Koishikawa Bunkyo-ku Tokyo 112-8088 JP
- 专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人地址： 4-6-10 Koishikawa Bunkyo-ku Tokyo 112-8088 JP
- 代理机构： Hoffmann Eitle
- 优先权： JP2013152677 20130723
- 国际公布： WO2015012210 20150129
- 主分类号： C07D491/048
- IPC分类号： C07D491/048 ; C07D493/04 ; C07D495/04 ; C07D513/04 ; C07F5/02 ; C07F7/22 ; A61K31/34 ; A61K31/381 ; A61K31/407 ; A61K31/429 ; A61K31/4355 ; A61K31/4985 ; A61K31/5025 ; A61K31/519 ; A61P1/04 ; A61P9/10 ; A61P31/10 ; C07B61/00
摘要：
A compound represented by the formula (I) or a salt thereof:
wherein a ring Z is a 5 to 6-membered heteroaromatic ring having one or two heteroatoms in the ring; X 1 is a hydrogen atom, a hydroxy group, a hydroxy C 1-6 alkyl group, -B(OH) 2 , a boronate ester group, a cyclic boronate ester group, a boranyl group, a cyclic boranyl group, -BF 3 M n1 , -Sn(R 12 )(R 13 )(R 14 ), a leaving group, a carboxy group, a formyl group, or -NR 16 R 17 ; and X 2 is a hydrogen atom or -CO 2 R 18 .
wherein a ring Z is a 5 to 6-membered heteroaromatic ring having one or two heteroatoms in the ring; X 1 is a hydrogen atom, a hydroxy group, a hydroxy C 1-6 alkyl group, -B(OH) 2 , a boronate ester group, a cyclic boronate ester group, a boranyl group, a cyclic boranyl group, -BF 3 M n1 , -Sn(R 12 )(R 13 )(R 14 ), a leaving group, a carboxy group, a formyl group, or -NR 16 R 17 ; and X 2 is a hydrogen atom or -CO 2 R 18 .
公开/授权文献
- EP3026054B1 HETERO-CONDENSED RING COMPOUND 公开/授权日：2019-03-06
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