发明公开
EP3030900A2 CORRELATION OF DISEASE ACTIVITY WITH CLONAL EXPANSIONS OF HUMAN PAPILLOMAVIRUS 16-SPECIFIC CD8+ T-CELLS IN PATIENTS WITH SEVERE EROSIVE ORAL LICHEN PLANUS 审中-公开
WITH人类克隆性疾病活性的相关性展开式患者乳头瘤病毒16特异性CD8 + T细胞与HEAVY糜烂口腔扁平苔藓

CORRELATION OF DISEASE ACTIVITY WITH CLONAL EXPANSIONS OF HUMAN PAPILLOMAVIRUS 16-SPECIFIC CD8+ T-CELLS IN PATIENTS WITH SEVERE EROSIVE ORAL LICHEN PLANUS
摘要:
A massive clonal expansion of activated CD8 + T-cells with increased frequency of HPV 16-specific CD8 + T-cells was discovered to be a characteristic of oral lichen planus (OLP), indicating a causal link between HPV infection and the dysimmune process. The invention relates to compositions and methods for the diagnosis and treatment of OLP patients.
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