The invention relates to a valve, comprising a valve housing (12), through which process medium can flow and in which a valve seat (17) surrounding a flow-through opening (16) is arranged, with which valve seat a valve element (18) arranged on a spindle (19) is associated in such a way that the valve element (18) can be moved by means of a setting stroke of the spindle (19) between a shut-off position, in which the valve element (18) lies tightly against the valve seat (17) in a pressure-medium-tight manner, and an open position, in which the valve element (18) is lifted from the valve seat (17), wherein a seal device (65), through which the spindle (19) reaches and which seals off the spindle passage, is accommodated in the valve housing (12), and comprising a valve drive (28), which has a drive housing (29) and a working wall (34), which is movably arrranged in the drive housing (29) and can be acted on by fluid pressure and produces the setting stroke of the spindle (19), and wherein a valve-housing interface (49) is arranged on the valve housing (12) and a drive-housing interface (50) is arranged on the drive housing (29), the valve-housing interface and drive-housing interface being provided for coupling the valve housing (12) and the drive housing (29). The drive housing (29) has a housing bottom (32), which is arranged before the working wall (34) and bounds a working chamber (35) for the working wall (34) on which the drive-housing interface (50) is located.