发明公开
EP3044334A4 PDGF AND VEGF APTAMERS HAVING IMPROVED STABILITY AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED DISEASES AND DISORDERS
审中-公开
PDGF-UND VEGF-APTAMERE MITERHÖHTERSTABILITÄTUND DEREN VERWENDUNG BEI DER BEHANDLUNG PDGF- UND VEGF-VERMITTELTER KRANKHEITEN UND LEIDEN
- 专利标题： PDGF AND VEGF APTAMERS HAVING IMPROVED STABILITY AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED DISEASES AND DISORDERS
- 专利标题（中）： PDGF-UND VEGF-APTAMERE MITERHÖHTERSTABILITÄTUND DEREN VERWENDUNG BEI DER BEHANDLUNG PDGF- UND VEGF-VERMITTELTER KRANKHEITEN UND LEIDEN
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申请号： EP14842475申请日： 2014-09-08
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公开(公告)号： EP3044334A4公开(公告)日： 2017-08-02
- 发明人: JANJIC NEBOJSA , DROLET DANIEL W , GELINAS AMY D , ZHANG CHI , VRKLJAN MICHAEL
- 申请人： SOMALOGIC INC
- 专利权人： SOMALOGIC INC
- 当前专利权人： SOMALOGIC INC
- 优先权： US201361875660 2013-09-09
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Aptamers having improved stability against nucleases that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF aptamer and a VEGF aptamer are provided. Pharmaceutical compositions comprising the aptamers and aptamer constructs are provided, as well as methods of treating conditions using the aptamers and aptamer constructs.
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