发明公开
EP3046920A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES
审中-公开
葡萄糖酰胺合成酶抑制剂用于治疗疾病
- 专利标题: GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES
- 专利标题(中): 葡萄糖酰胺合成酶抑制剂用于治疗疾病
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申请号: EP14789439.8申请日: 2014-09-19
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公开(公告)号: EP3046920A1公开(公告)日: 2016-07-27
- 发明人: WANG, Bing , CHU, Daniel , BRIDGES, Alexander, James
- 申请人: BioMarin Pharmaceutical Inc.
- 申请人地址: 105 Digital Drive Novato, CA 94949 US
- 专利权人: BioMarin Pharmaceutical Inc.
- 当前专利权人: BioMarin Pharmaceutical Inc.
- 当前专利权人地址: 105 Digital Drive Novato, CA 94949 US
- 代理机构: Jones Day
- 优先权: US201361880752P 20130920
- 国际公布: WO2015042397 20150326
- 主分类号: C07D405/14
- IPC分类号: C07D405/14 ; C07D319/18 ; C07D405/12 ; C07D407/12 ; C07D417/12 ; C07D307/79 ; C07D409/12 ; C07D213/64 ; C07D295/12 ; C07D309/10 ; C07D311/12 ; C07D413/12 ; C07D265/30 ; C07D205/04 ; C07D333/16
摘要:
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).
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