发明公开
EP3049440A1 V-C-FC-V-C ANTIBODY 审中-公开
V-C-FC-V-C抗体

  • 专利标题: V-C-FC-V-C ANTIBODY
  • 专利标题(中): V-C-FC-V-C抗体
  • 申请号: EP14782039.3
    申请日: 2014-09-25
  • 公开(公告)号: EP3049440A1
    公开(公告)日: 2016-08-03
  • 发明人: MICHAELS, Mark, L.BORGES, Luis, G.YAN, Wei
  • 申请人: Amgen Inc.
  • 申请人地址: One Amgen Center Drive Thousand Oaks, California 91320-1799 US
  • 专利权人: Amgen Inc.
  • 当前专利权人: Amgen Inc.
  • 当前专利权人地址: One Amgen Center Drive Thousand Oaks, California 91320-1799 US
  • 代理机构: Schiweck, Weinzierl & Koch
  • 优先权: US201361882428P 20130925
  • 国际公布: WO2015048272 20150402
  • 主分类号: C07K16/28
  • IPC分类号: C07K16/28 C07K16/32
V-C-FC-V-C ANTIBODY
摘要:
Described herein is a dimeric, bispecific antibody format. Each polypeptide chain of the dimer comprises an immunoglobulin variable region, an immunoglobulin constant region, an Fc polypeptide chain, another immunoglobulin variable region, and another immunoglobulin constant region. Also described are methods of making and using such antibodies.
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