发明公开
EP3067346A1 PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF
审中-公开
吡哆醛羟基 - 氨基丁二酸二十一烷酸乙酯酶HEMMER在VERWENDUNGSVERFAHRENDAFÜR
- 专利标题: PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF
- 专利标题(中): 吡哆醛羟基 - 氨基丁二酸二十一烷酸乙酯酶HEMMER在VERWENDUNGSVERFAHRENDAFÜR
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申请号: EP16150961.7申请日: 2011-11-15
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公开(公告)号: EP3067346A1公开(公告)日: 2016-09-14
- 发明人: VAN DUZER, John, H. , MAZITSCHEK, Ralph , DING, Yanbing , YU, Nan , CAO, Yun , LIU, Yong
- 申请人: Acetylon Pharmaceuticals, Inc.
- 申请人地址: 70 Fargo Street, Suite 205 Boston, MA 02210 US
- 专利权人: Acetylon Pharmaceuticals, Inc.
- 当前专利权人: Acetylon Pharmaceuticals, Inc.
- 当前专利权人地址: 70 Fargo Street, Suite 205 Boston, MA 02210 US
- 代理机构: Boult Wade Tennant
- 优先权: US414158P 20101116; US201161503286P 20110630
- 主分类号: C07D239/12
- IPC分类号: C07D239/12 ; C07D239/16 ; C07D409/12 ; A61K31/495 ; A61P25/00 ; C07D403/12 ; C07D401/14 ; C07D401/12 ; C07D405/12 ; C07D239/42
摘要:
The present invention relates to novel pyrimidine hydroxy amide compounds, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.
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