- 专利标题： NON-HUMAN ANIMALS HAVING A HUMANIZED B-CELL ACTIVATING FACTOR GENE
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申请号： EP14803022.4申请日： 2014-11-10
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公开(公告)号： EP3071024B1公开(公告)日： 2018-09-05
- 发明人: MCWHIRTER, John , GURER, Cagan , MACDONALD, Lynn , MURPHY, Andrew J.
- 申请人： Regeneron Pharmaceuticals, Inc.
- 申请人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- 专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- 代理机构： J A Kemp
- 优先权： US201361905983P 20131119
- 国际公布： WO2015077071 20150528
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; C07K14/54 ; C07K14/705
摘要：
Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized B-cell activating factor gene. Non-human animals and cells that express a human or humanized B-cell activating factor protein from an endogenous B-cell activating factor locus are described.
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