- 专利标题： NON-HUMAN ANIMALS HAVING A HUMANIZED A PROLIFERATION-INDUCING LIGAND GENE
-
申请号： EP14835599.3申请日： 2014-11-10
-
公开(公告)号： EP3071025B1公开(公告)日： 2018-10-10
- 发明人: MCWHIRTER, John , GURER, Cagan , MACDONALD, Lynn , MURPHY, Andrew J.
- 申请人： Regeneron Pharmaceuticals, Inc.
- 申请人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- 专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- 代理机构： J A Kemp
- 优先权： US201361905986P 20131119
- 国际公布： WO2015077072 20150528
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; C07K14/705 ; C12N15/85 ; C07K14/47 ; G01N33/50
摘要：
Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized a proliferation-inducing ligand gene. Non-human animals and cells that express a human or humanized a proliferation-inducing ligand protein from an endogenous a proliferation-inducing ligand locus are described.
公开/授权文献
信息查询
