A system and method for managing treatment of a disorder of a person are disclosed. Data from multiple sources is collected in a data warehouse by a server computer. The data is associated with the disorder, and the sources including a clinical data source and a real-time monitoring source associated with the person. The collected data is normalized against a population of persons sharing the disorder. The normalized data is then associated with the person to generate a treatment regime of the disorder. A compliance by the person with the treatment regime is then calculated based on operational metrics for the population and the data collected from the plurality of sources.