Devices, systems, and techniques are provided for performing human fingerprint detection and authentication for authenticating a request to access a locked mobile device equipped with a fingerprint detection module. In one aspect, responsive to detecting a contact from an object with the fingerprint detection module, described technique can be used to determines whether the contact from the object is from human skin. When determined that the detected contact from the object is from human skin, a presence of a human fingerprint can be detected from the object making contact. The detected fingerprint data can be obtained from the object and compared against stored fingerprint profiles associated with an authorized user of the locked mobile device. Based on the comparing, the request to access the locked mobile device can be granted.