In an embodiment, a method includes performing a turbine combustor diagnostic routine including operating a first turbine combustor of a plurality of turbine combustors at a substantially steady state of combustion; adjusting an operational parameter of the first turbine combustor to cause a change in combustion products produced by the first turbine combustor; identifying a first sensor response of a first subset of a plurality of sensors disposed within or downstream from a turbine fluidly coupled to the turbine combustor, the first sensor response being indicative of the change in the combustion products, and wherein the first subset comprises one or more first sensors; correlating the first subset of sensors with the first turbine combustor; and diagnosing a condition of the first subset of the plurality of sensors, the first turbine combustor, or a combination thereof, based on the first sensor response.