发明公开
- 专利标题: SOLUBLE GUANYLATE CYCLASE ACTIVATORS
- 专利标题(中): LÖSLICHEGUANYLAT-CYCLASE-AKTIVATOREN
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申请号: EP14869616申请日: 2014-12-05
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公开(公告)号: EP3079700A4公开(公告)日: 2017-07-19
- 发明人: HAN XIAOQING , WHITEHEAD ALAN , RAGHAVAN SUBHAREKHA , CERNAK TIMOTHY A , DREHER SPENCER , GROEPER JONATHAN , GUO JIAN , ZHANG YONG
- 申请人: MERCK SHARP & DOHME
- 专利权人: MERCK SHARP & DOHME
- 当前专利权人: MERCK SHARP & DOHME
- 优先权: US201361914568 2013-12-11
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K45/06 ; A61P3/10 ; A61P7/02 ; A61P9/00 ; A61P13/12 ; C07D519/00
摘要:
A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (" cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceuticall acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula I or a pharmaceutically acceptable salt thereof.
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