发明公开
EP3099784A1 IMPROVED CARBON DIOXIDE FIXATION VIA BYPASSING FEEDBACK REGULATION
审中-公开
VERBESSERTE KOHLENDIOXIDFIXIERUNG MITTELSRÜCKKOPPLUNGSREGULIERUNGSUMGEHUNG
- 专利标题: IMPROVED CARBON DIOXIDE FIXATION VIA BYPASSING FEEDBACK REGULATION
- 专利标题(中): VERBESSERTE KOHLENDIOXIDFIXIERUNG MITTELSRÜCKKOPPLUNGSREGULIERUNGSUMGEHUNG
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申请号: EP15743189.1申请日: 2015-01-30
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公开(公告)号: EP3099784A1公开(公告)日: 2016-12-07
- 发明人: HUO, Yi-Xin , SCHILLING, Benjamin , RABIZADEH, Shahrooz
- 申请人: Easel Biotechnologies LLC
- 申请人地址: 9920 Jefferson Boulevard Culver City, California 90232 US
- 专利权人: Easel Biotechnologies LLC
- 当前专利权人: Easel Biotechnologies LLC
- 当前专利权人地址: 9920 Jefferson Boulevard Culver City, California 90232 US
- 代理机构: Wynne-Jones, Laine and James LLP
- 优先权: US201461933422P 20140130
- 国际公布: WO2015117019 20150806
- 主分类号: C12N1/21
- IPC分类号: C12N1/21 ; C12N9/10 ; C12N15/63 ; C12P1/02 ; C12P5/02 ; C12P7/16
摘要:
Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
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