发明公开
EP3102679A2 MICRO-RNAS AND COMPOSITIONS COMPRISING SAME FOR THE TREATMENT AND DIAGNOSIS OF SEROTONIN-, ADRENALIN-, NORADRENALIN-, GLUTAMATE-, AND CORTICOTROPIN-RELEASING HORMONE- ASSOCIATED MEDICAL CONDITIONS
审中-公开
微小RNA和组合物用于治疗和血清素，肾上腺素，去甲肾上腺素，谷氨酸诊断和促肾上腺皮质激素释放激素介导的医学莱顿
- 专利标题： MICRO-RNAS AND COMPOSITIONS COMPRISING SAME FOR THE TREATMENT AND DIAGNOSIS OF SEROTONIN-, ADRENALIN-, NORADRENALIN-, GLUTAMATE-, AND CORTICOTROPIN-RELEASING HORMONE- ASSOCIATED MEDICAL CONDITIONS
- 专利标题（中）： 微小RNA和组合物用于治疗和血清素，肾上腺素，去甲肾上腺素，谷氨酸诊断和促肾上腺皮质激素释放激素介导的医学莱顿
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申请号： EP15710264.1申请日： 2015-02-05
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公开(公告)号： EP3102679A2公开(公告)日： 2016-12-14
- 发明人: CHEN, Alon , ISSLER, Orna
- 申请人： Yeda Research and Development Co., Ltd.
- 申请人地址： at the Weizmann Institute of Science P.O. Box 95 7610002 Rehovot IL
- 专利权人： Yeda Research and Development Co., Ltd.
- 当前专利权人： Yeda Research and Development Co., Ltd.
- 当前专利权人地址： at the Weizmann Institute of Science P.O. Box 95 7610002 Rehovot IL
- 代理机构： Dennemeyer & Associates S.A.
- 优先权： US201461935912P 20140205
- 国际公布： WO2015118537 20150813
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; A61K31/7088
摘要：
A method of treating a bipolar disorder in a subject in need thereof is disclosed. The method comprising administering to the subject sa therapeutically effective amount of a miR-135, a precursor thereof or a nucleic acid molecule encoding said miR-135 or said precursor thereof, thereby treating the bipolar disorder. Methods of diagnosing a mood disorder in a human subject and of monitoring treatment of an anti-depressant drug or a medicament for the treatment of a mood disorder are also disclosed.
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