发明公开
EP3109232A4 OPTICALLY ACTIVE FORM OF MEPENZOLATE, AND AMELIORATING AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE WHICH CONTAINS SAME AS ACTIVE INGREDIENT
审中-公开
OPTISCH AKTIVE FORM VON MEPENZOLAT UND LINDERUNGSMITTELFÜRCHRONISCH-OBSTRUKTIVE LUNGENERKRANKUNG DAMIT ALS WIRKSTOFF
- 专利标题： OPTICALLY ACTIVE FORM OF MEPENZOLATE, AND AMELIORATING AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE WHICH CONTAINS SAME AS ACTIVE INGREDIENT
- 专利标题（中）： OPTISCH AKTIVE FORM VON MEPENZOLAT UND LINDERUNGSMITTELFÜRCHRONISCH-OBSTRUKTIVE LUNGENERKRANKUNG DAMIT ALS WIRKSTOFF
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申请号： EP14882606申请日： 2014-06-16
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公开(公告)号： EP3109232A4公开(公告)日： 2017-06-28
- 发明人: MIZUSHIMA TORU
- 申请人： LTT BIO-PHARMA CO LTD
- 专利权人： LTT BIO-PHARMA CO LTD
- 当前专利权人： LTT BIO-PHARMA CO LTD
- 优先权： JP2014027539 2014-02-17
- 主分类号： C07D211/42
- IPC分类号： C07D211/42 ; A61K31/452 ; A61P11/00 ; A61P11/08 ; A61P29/00
摘要：
An optically active form of mepenzolate bromide is provided. An agent for ameliorating chronic obstructive pulmonary disease that contains the optically active form as an active ingredient and is based on a bronchodilator effect and an anti-inflammatory effect is also provided. (3R)- or (3S)-3-[(hydroxy)(diphenyl)acetoxy]-1,1-dimethylpiperidinium bromide (hereinafter referred to as "(R)- or (S)-mepenzolate bromide") is provided. An agent for ameliorating chronic obstructive pulmonary disease that contains the (R)- or (S)-mepenzolate bromide as an active ingredient is provided. Furthermore, an agent for ameliorating chronic obstructive pulmonary disease whose mode of administration is airway administration or inhalation administration is provided.
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