发明公开
EP3112361A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
审中-公开
APOPTOSEINDUKTOREN ZUR BEHANDLUNG冯KREBS SOWIE VON IMMUN- UND AUTOIMMUNERKRANKUNGEN
- 专利标题: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
- 专利标题(中): APOPTOSEINDUKTOREN ZUR BEHANDLUNG冯KREBS SOWIE VON IMMUN- UND AUTOIMMUNERKRANKUNGEN
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申请号: EP16175661.4申请日: 2009-12-04
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公开(公告)号: EP3112361A1公开(公告)日: 2017-01-04
- 发明人: BRUNCKO, Milan , DAI, Yujia , DING, Hong , DOHERTY, George, A. , ELMORE, Steven, W. , HASVOLD, Lisa , HEXAMER, Laura , KUNZER, Aaron, R. , MANTEI, Robert, A. , MCCLELLAN, William, J. , PARK, Chang, H. , PARK, Cheol-Min , PETROS, Andrew, M. , SONG, Xiaohong , SOUERS, Andrew, J. , SULLIVAN, Gerard, M. , TAO, Zhi-Fu , WANG, Gary, T. , WANG, Le , WANG, Xilu , WENDT, Michael, D. , CZABOTAR, Peter Edward , LESSENE, Guillaume Laurent , COLMAN, Peter Malcom
- 申请人: AbbVie Inc. , The Walter and Eliza Hall Institute of Medical Research
- 申请人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人: AbbVie Inc.,The Walter and Eliza Hall Institute of Medical Research
- 当前专利权人: AbbVie Inc.,The Walter and Eliza Hall Institute of Medical Research
- 当前专利权人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构: Modiano, Micaela Nadia
- 优先权: US119844P 20081204
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D405/14 ; C07D213/74 ; C07D309/04 ; C07D213/84 ; C07D235/06 ; C07D405/12 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D277/24 ; C07D209/08 ; C07D211/58 ; C07D295/30 ; A61P35/00 ; A61K31/496 ; C07D231/56
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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