发明公开
EP3122774A2 USES OF PARASITE MACROPHAGE MIGRATION INHIBITORY FACTORS
审中-公开
VERWENDUNG VON MIGRATIONSHEMMUNGSFAKTORENPARASITÄRERMAKROPHAGEN
- 专利标题： USES OF PARASITE MACROPHAGE MIGRATION INHIBITORY FACTORS
- 专利标题（中）： VERWENDUNG VON MIGRATIONSHEMMUNGSFAKTORENPARASITÄRERMAKROPHAGEN
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申请号： EP15711775.5申请日： 2015-03-24
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公开(公告)号： EP3122774A2公开(公告)日： 2017-02-01
- 发明人: BUCALA, Richard , GEALL, Andrew
- 申请人： Yale University , GlaxoSmithKline Biologicals S.A.
- 申请人地址： Two Whitney Avenue New Haven, CT 06510 US
- 专利权人： Yale University,GlaxoSmithKline Biologicals S.A.
- 当前专利权人： Yale University,GlaxoSmithKline Biologicals S.A.
- 当前专利权人地址： Two Whitney Avenue New Haven, CT 06510 US
- 代理机构： Carpmaels & Ransford LLP
- 优先权： EP14161614 20140325
- 国际公布： WO2015144732 20151001
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; C07K14/435 ; C07K14/44
摘要：
This invention relates to compositions (e.g. vaccine compositions) which can be used to provide a subject with protective immunity against a parasite infection. The compositions comprise: (i) an immunologically effective amount of a nucleic acid (e.g. a nucleic acid-based vaccine) comprising a sequence which encodes a parasite macrophage migration inhibitory factor (MIF) antigen; (ii) a parasite MIF antigen; or (iii) an antibody which specifically binds to a parasite MIF antigen. The compositions may be used to treat infections and diseases caused by parasitic protozoans, such as a Plasmodium parasite, or parasitic helminths.
公开/授权文献
- EP3122774B1 USES OF PARASITE MACROPHAGE MIGRATION INHIBITORY FACTORS 公开/授权日：2020-11-04
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