发明公开
EP3132803A3 PREVENTIVE OR THERAPEUTIC AGENT FOR PAIN ASSOCIATED WITH HERPES ZOSTER IN ACUTE PHASE
审中-公开
预防性或治疗性药物与急性期疱疹相关的疼痛
- 专利标题： PREVENTIVE OR THERAPEUTIC AGENT FOR PAIN ASSOCIATED WITH HERPES ZOSTER IN ACUTE PHASE
- 专利标题（中）： 预防性或治疗性药物与急性期疱疹相关的疼痛
-
申请号： EP16187888.9申请日： 2011-11-02
-
公开(公告)号： EP3132803A3公开(公告)日： 2017-04-26
- 发明人: Inoue, Kazuhide , Tsuda, Makoto , Matsumura, Yuta
- 申请人： Kyushu University , Nippon Chemiphar Co., Ltd.
- 申请人地址： 6-10-1 Hakozaki Higashi-ku Fukuoka-shi, Fukuoka 812-8581 JP
- 专利权人： Kyushu University,Nippon Chemiphar Co., Ltd.
- 当前专利权人： Kyushu University,Nippon Chemiphar Co., Ltd.
- 当前专利权人地址： 6-10-1 Hakozaki Higashi-ku Fukuoka-shi, Fukuoka 812-8581 JP
- 代理机构： Hiebl, Inge Elisabeth
- 优先权： JP2010248173 20101105
- 主分类号： A61K45/00
- IPC分类号： A61K45/00 ; A61K31/135 ; A61K31/138 ; A61K31/15 ; A61K31/335 ; A61K31/343 ; A61K31/451 ; A61K31/4525 ; A61K31/495 ; A61K31/55 ; A61K31/551 ; A61P29/00 ; C07D223/28 ; C07D307/87 ; C07D313/12 ; C07D405/12 ; C07D413/10
摘要：
A P2X 4 receptor antagonist such as paroxetine, a diazepinedione derivative having the following formula (IX) is used as an agent for preventing or treating zoster-associated pain in acute phase:
wherein R 1 is hydrogen, a C 1-8 alkyl group, or the like;
each of R 2 and R 3 is hydrogen, a C 1-8 alkyl group, or the like;
each of R 4 and R 5 is hydrogen or the like; and
W is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.
wherein R 1 is hydrogen, a C 1-8 alkyl group, or the like;
each of R 2 and R 3 is hydrogen, a C 1-8 alkyl group, or the like;
each of R 4 and R 5 is hydrogen or the like; and
W is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.
公开/授权文献
信息查询
