A staple cartridge is disclosed. The staple cartridge comprises a cartridge body including staple cavities and staples removably stored in the staple cavities. The staple cartridge further comprises a firing member configured to eject the staples from the staple cavities. The staples and staple cavities include features which reduce friction forces between the staples and the staple cavities when the firing member ejects the staples from the staple cavities. Each of the staples comprises a base including a drive portion and staple legs extending from the base and, in at least one instance, each of the staple cavities includes a proximal guide and a distal guide configured to guide the staple legs of the staple positioned therein as it is ejected from the staple cavity. In certain instances, each of the staple cavities further includes an intermediate guide offset from the proximal guide and the distal guide.