Systems, methods, and apparatuses for debriding a tissue site are described. The system includes a manifold (108)and a cover (102) adapted to form a sealed space over the tissue site for providing negative pressure. The system also includes a debridement tool (110) positioned between the manifold and the tissue site. The debridement cool having a tissue-facing surface and a plurality of holes separated from each other by walls. The walls have transverse surfaces extending between the tissue-facing surface and an opposite surface that form, cutting edges. The holes have a perforation shape factor that allows the holes to collapse from a relaxed position, to a contracted position in response to the application and removal of negative pressure from, the sealed space. The cutting edges debride the tissue site in response to movement between, the relaxed position and the contracted position.