发明公开
EP3139952A1 COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONS
审中-公开
ZUSAMMENSETZUNGEN，VERFAHREN UND VERWENDUNGENFÜRTHERMISCH STABILE，HUMANE PAPILLOMAVIRUSFORMULIERUNGEN
- 专利标题： COMPOSITIONS, METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONS
- 专利标题（中）： ZUSAMMENSETZUNGEN，VERFAHREN UND VERWENDUNGENFÜRTHERMISCH STABILE，HUMANE PAPILLOMAVIRUSFORMULIERUNGEN
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申请号： EP15722018.7申请日： 2015-05-06
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公开(公告)号： EP3139952A1公开(公告)日： 2017-03-15
- 发明人: RANDOLPH, Theodore , GARCEA, Robert , HASSETT, Kimberly, J.
- 申请人： The Regents of the University of Colorado, a body corporate
- 申请人地址： 1800 Grant Street, 8th Floor Denver, CO 80203 US
- 专利权人： The Regents of the University of Colorado, a body corporate
- 当前专利权人： The Regents of the University of Colorado, a body corporate
- 当前专利权人地址： 1800 Grant Street, 8th Floor Denver, CO 80203 US
- 代理机构： Vossius & Partner Patentanwälte Rechtsanwälte mbB
- 优先权： US201461989365P 20140506
- 国际公布： WO2015171810 20151112
- 主分类号： A61K39/08
- IPC分类号： A61K39/08
摘要：
Embodiments of the present invention provide for novel compositions and methods for making and using a thermally stable human papilloma virus (HPV) formulation or other stabilized multimeric virus formulation. Certain embodiments concern lyophilizing HPV formulations in the presence or absence of adjuvants. Other embodiments concern lypophilizing HPV capsomere vaccines in order to increase stability of an immunogenic composition against HPV infection for storage, delivery and use. In yet other embodiments, a single immunogenic composition can include a thermally stable formulation of multiple virus serotypes.
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