- 专利标题： 1-(CYCLOPENT-2-EN-1-YL)-3-(2-HYDROXY-3-(ARYLSULFONYL)PHENYL)UREA DERIVATIVES AS CXCR2 INHIBITORS
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申请号： EP15726090.2申请日： 2015-05-27
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公开(公告)号： EP3148963B1公开(公告)日： 2018-06-13
- 发明人: CHEN, Weichun , IGBOKO, Ebere F , LIN, Xichen , LU, Hongfu , REN, Feng , WREN, Paul Bryan , XU, Zhongmiao , YANG, Ting , ZHU, Lingdong
- 申请人： GlaxoSmithKline Intellectual Property Development Limited
- 申请人地址： 980 Great West Road Brentford Middlesex TW8 9GS GB
- 专利权人： GlaxoSmithKline Intellectual Property Development Limited
- 当前专利权人： GlaxoSmithKline Intellectual Property Development Limited
- 当前专利权人地址： 980 Great West Road Brentford Middlesex TW8 9GS GB
- 代理机构： Sewell, Richard Charles
- 优先权： PCT/CN2014/000545 20140529; PCT/CN2014/083380 20140731; PCT/CN2015/077947 20150430
- 国际公布： WO2015181186 20151203
- 主分类号： C07C211/56
- IPC分类号： C07C211/56 ; C07D207/10 ; C07D211/54 ; C07D213/34 ; C07D233/64 ; C07D239/26 ; C07C275/30 ; C07D295/135 ; C07D305/06 ; C07D307/18 ; C07D309/08 ; C07D471/04 ; C07D487/04 ; A61K31/17 ; A61P11/00 ; A61P29/00
摘要：
The invention relates to 1-(3-sulfonylphenyl)-3-(cyclopent-2-en-1-yl)urea derivatives, and their use in treating or preventing diseases and conditions mediated by the CXCR2 receptor. In addition, the invention relates to compositions containing the derivatives and processes for their preparation.
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