发明公开
EP3149001A1 NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHIBITORS
审中-公开
天然维生素DYEN VERWENDUNG ALS MALT1-HEMMER
- 专利标题： NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHIBITORS
- 专利标题（中）： 天然维生素DYEN VERWENDUNG ALS MALT1-HEMMER
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申请号： EP15733899.7申请日： 2015-05-27
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公开(公告)号： EP3149001A1公开(公告)日： 2017-04-05
- 发明人: PISSOT SOLDERMANN, Carole , QUANCARD, Jean , SCHLAPBACH, Achim , SIMIC, Oliver , TINTELNOT-BLOMLEY, Marina , ZOLLER, Thomas
- 申请人： Novartis AG
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： von Sprecher, Georg
- 优先权： EP14170408 20140528
- 国际公布： WO2015181747 20151203
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61P29/00 ; A61P35/00 ; A61P37/00
摘要：
The present invention describes new pyrazolo-pyrimidine derivatives which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.
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