发明公开
EP3156404A1 NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
审中-公开
新建连接抑制剂YAP / TAZ TEAD相互作用和用途恶性间皮瘤治疗
- 专利标题： NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
- 专利标题（中）： 新建连接抑制剂YAP / TAZ TEAD相互作用和用途恶性间皮瘤治疗
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申请号： EP15306651.9申请日： 2015-10-15
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公开(公告)号： EP3156404A1公开(公告)日： 2017-04-19
- 发明人: BARTH, Martine , CONTAL, Sylvie , MONTALBETTI, Christian , SPITZER, Luc
- 申请人： INVENTIVA
- 申请人地址： 50, rue de Dijon 21121 Daix FR
- 专利权人： INVENTIVA
- 当前专利权人： INVENTIVA
- 当前专利权人地址： 50, rue de Dijon 21121 Daix FR
- 代理机构： Nevant, Marc
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; A61K31/428 ; C07D275/06 ; A61P35/00
摘要：
The invention relates to compounds of formula I
wherein R1, R2, R3, R4, R5 are as defined in the description.
The compounds of formula I are useful for the treatment of diseases where inhibition of the YAP/TAZ-TEAD interaction is required.
wherein R1, R2, R3, R4, R5 are as defined in the description.
The compounds of formula I are useful for the treatment of diseases where inhibition of the YAP/TAZ-TEAD interaction is required.
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