- 专利标题： OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL
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申请号： EP15809987申请日： 2015-06-17
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公开(公告)号： EP3158338A4公开(公告)日： 2017-12-06
- 发明人: COHEN ADAM E , HOCHBAUM DANIEL , ZOU PENG , FARHI SAMOUIL LEON , CAMPBELL ROBERT EARL , ZHAO YONGXIN , HARRISON DANIEL JED
- 申请人： HARVARD COLLEGE , UNIV ALBERTA
- 专利权人： HARVARD COLLEGE,UNIV ALBERTA
- 当前专利权人： HARVARD COLLEGE,UNIV ALBERTA
- 优先权： US201462013775 2014-06-18
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; G01N33/50 ; G01N33/53
摘要：
Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
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