发明公开
- 专利标题: USE OF METALLOPROTEINASE INHIBITORS AGAINST BACTERIAL INFECTIONS
- 专利标题(中): 金属蛋白酶抑制剂抗细菌感染的应用
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申请号: EP15734655.2申请日: 2015-07-03
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公开(公告)号: EP3164151A1公开(公告)日: 2017-05-10
- 发明人: SALZIG, Mark , VILCINSKAS, Andreas , FISCHER, Rainer
- 申请人: Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V.
- 申请人地址: Hansastrasse 27C 80686 München DE
- 专利权人: Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V.
- 当前专利权人: Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V.
- 当前专利权人地址: Hansastrasse 27C 80686 München DE
- 代理机构: Roth, Andy Stefan
- 优先权: EP14175566 20140703
- 国际公布: WO2016001410 20160107
- 主分类号: A61K38/57
- IPC分类号: A61K38/57 ; A61K45/06 ; C07K14/81 ; A61P31/04
摘要:
A composition comprising as components a polypeptide IMPIα (including wild type) and/or a polypeptide IMPIα-fusion and at least one antibiotic compound, in particular an aminoglycoside antibiotic, and/or at least one bactericidal compound, wherein the polypeptides, the at least one antibiotic and the at least one bactericidal compound is present in the composition in concentrations which exhibit in combination a synergistic effect against resistant bacteria.
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