发明公开
- 专利标题: PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP
- 专利标题(中): 吡啶二酮麻醉四氢呋喃 - 甲基丙烯酸酯
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申请号: EP15818440.8申请日: 2015-07-06
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公开(公告)号: EP3168219A1公开(公告)日: 2017-05-17
- 发明人: HAGINOYA, Noriyasu , SUZUKI, Takashi , HAYAKAWA, Miho , OTA, Masahiro , TSUKADA, Tomoharu , KOBAYASHI, Katsuhiro , ANDO, Yosuke , JIMBO, Takeshi , NAKAMURA, Koichi
- 申请人: Daiichi Sankyo Company, Limited
- 申请人地址: 3-5-1, Nihonbashi Honcho Chuo-ku Tokyo 103-8426 JP
- 专利权人: Daiichi Sankyo Company, Limited
- 当前专利权人: Daiichi Sankyo Company, Limited
- 当前专利权人地址: 3-5-1, Nihonbashi Honcho Chuo-ku Tokyo 103-8426 JP
- 代理机构: Wallace, Sheila Jane
- 优先权: JP2014139628 20140707
- 国际公布: WO2016006706 20160114
- 主分类号: C07D405/14
- IPC分类号: C07D405/14 ; A61K31/444 ; A61K31/496 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; A61P35/00 ; A61P35/02 ; A61P35/04 ; A61P43/00 ; C07D409/14
摘要:
It is intended to provide a novel compound or a salt thereof, or crystals of the compound or the salt, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
[Solution]
The present invention provides a pyridone derivative having a tetrahydropyranylmethyl group represented by the following formula (I) having various substituents, or a salt thereof, or crystals of the compound or the salt (wherein R 1 , R 2 , R 3 , R 4 , R 5 , W, X, Y, and Z are each as defined in the specification).
[Solution]
The present invention provides a pyridone derivative having a tetrahydropyranylmethyl group represented by the following formula (I) having various substituents, or a salt thereof, or crystals of the compound or the salt (wherein R 1 , R 2 , R 3 , R 4 , R 5 , W, X, Y, and Z are each as defined in the specification).
公开/授权文献
- EP3168219B1 PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP 公开/授权日:2021-03-31
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