发明公开
EP3169356A1 RECOMBINANT LISTERIA STRAIN EXPRESSING HETEROLOGOUS ANTIGEN FUSION PROTEINS AND METHODS OF USE THEREOF
审中-公开
重组LISTERIASTAMM为融合蛋白异种抗原表达及其使用方法
- 专利标题: RECOMBINANT LISTERIA STRAIN EXPRESSING HETEROLOGOUS ANTIGEN FUSION PROTEINS AND METHODS OF USE THEREOF
- 专利标题(中): 重组LISTERIASTAMM为融合蛋白异种抗原表达及其使用方法
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申请号: EP15822487.3申请日: 2015-07-17
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公开(公告)号: EP3169356A1公开(公告)日: 2017-05-24
- 发明人: WALLECHA, Anu , PETIT, Robert , ELLENHORN, Joshua , DIAMOND, Don J.
- 申请人: Advaxis, Inc. , City of Hope
- 申请人地址: 305 College Road East Princeton, NJ 08540 US
- 专利权人: Advaxis, Inc.,City of Hope
- 当前专利权人: Advaxis, Inc.,City of Hope
- 当前专利权人地址: 305 College Road East Princeton, NJ 08540 US
- 代理机构: Bentham, Andrew
- 优先权: US201462026085P 20140718
- 国际公布: WO2016011353 20160121
- 主分类号: A61K39/02
- IPC分类号: A61K39/02 ; A61K35/74 ; A61K39/12 ; A61P35/00
摘要:
Disclosed herein are recombinant nucleic acids encoding tumor antigens fused to immunogenic polypeptides and recombinant Listeria strains comprising the same, methods of preparing same, and methods of inducing an immune response, and treating, inhibiting, or suppressing cancer or tumors comprising administering same.
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