Provided is a vehicle body structure equipped with a frame (1) and a body (11), wherein a spare tire (7) is fixed to the frame (1) of a vehicle (10). Further, a tank (3) that stores an additive for exhaust purification of the vehicle (10) is disposed between the frame (1) and an outer panel (4) forming an outer surface of the body (11), behind a wheel house (6) of the vehicle (10) and above a bottom surface (31) of the spare tire (7).