发明公开
EP3174879A1 SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C
有权
取代的OXETANES及其作为CATHEPSIN抑制剂的用途C
- 专利标题： SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C
- 专利标题（中）： 取代的OXETANES及其作为CATHEPSIN抑制剂的用途C
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申请号： EP15739650.8申请日： 2015-07-28
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公开(公告)号： EP3174879A1公开(公告)日： 2017-06-07
- 发明人: GRAUERT, Matthias , ANDERSKEWITZ, Ralf , BIXENMANN, Achim , GRUNDL, Marc , HAEBEL, Peter Wilhelm , PAUTSCH, Alexander
- 申请人： Boehringer Ingelheim International GmbH
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构： Simon, Elke Anna Maria
- 优先权： EP14179458 20140801
- 国际公布： WO2016016242 20160204
- 主分类号： C07D471/08
- IPC分类号： C07D471/08 ; A61K31/439 ; A61P11/00
摘要：
This invention relates to a compound of formula I and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
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