发明公开
- 专利标题: MODIFIED ALGINATES FOR ANTI-FIBROTIC MATERIALS AND APPLICATIONS
- 专利标题(中): 改良抗生素抗菌药物
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申请号: EP15750880.5申请日: 2015-08-03
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公开(公告)号: EP3174906A1公开(公告)日: 2017-06-07
- 发明人: VEGAS, Arturo J. , DOLOFF, Joshua C. , VEISEH, Omid , MA, Minglin , LANGER, Robert S. , ANDERSON, Daniel G.
- 申请人: Massachusetts Institute Of Technology , The Children's Medical Center Corporation
- 申请人地址: 77 Massachusetts Avenue Cambridge, MA 02139 US
- 专利权人: Massachusetts Institute Of Technology,The Children's Medical Center Corporation
- 当前专利权人: Massachusetts Institute Of Technology,The Children's Medical Center Corporation
- 当前专利权人地址: 77 Massachusetts Avenue Cambridge, MA 02139 US
- 代理机构: Potter Clarkson LLP
- 优先权: US201462032148P 20140801; US201562180415P 20150616
- 国际公布: WO2016019391 20160204
- 主分类号: C08B37/00
- IPC分类号: C08B37/00 ; A61K47/36 ; C12N5/00 ; C12N5/071
摘要:
Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
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