发明公开
- 专利标题： COMPOSITIONS FOR STABILIZING AND DELIVERING PROTEINS
- 专利标题（中）： 稳定和提供蛋白质的组合物
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申请号： EP15756295.0申请日： 2015-08-14
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公开(公告)号： EP3179985A1公开(公告)日： 2017-06-21
- 发明人: MATHIOWITZ, Edith , FURTADO, Stacia , EGILMEZ, Nejat , CONWAY, Thomas
- 申请人： Brown University , Therapyx, Inc.
- 申请人地址： 47 George Street Providence, RI 02912 US
- 专利权人： Brown University,Therapyx, Inc.
- 当前专利权人： Brown University,Therapyx, Inc.
- 当前专利权人地址： 47 George Street Providence, RI 02912 US
- 代理机构： Hutter, Anton
- 优先权： US201462037492P 20140814
- 国际公布： WO2016025911 20160218
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K38/00 ; A61K39/00 ; A61K9/16 ; A61K9/19
摘要：
Compositions for stabilizing and delivering proteins and/or other bioactive agents are disclosed. The bioactive agents are embedded or encapsulated in a crystalline matrix. Typically the bioactive agents are in the form of micro- or nanoparticles. The crystalline matrix confers enhanced stability to the agents embedded therein relative to other microparticulate or nanoparticulate bioactive agents. The carriers are especially useful for stabilizing bioactive macromolecules, such as proteins.
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