发明公开
- 专利标题: CANCER DIAGNOSIS AND THERAPY
- 专利标题(中): 癌症诊断和治疗
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申请号: EP15832111.7申请日: 2015-08-12
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公开(公告)号: EP3180000A1公开(公告)日: 2017-06-21
- 发明人: BAILLIE, Ranui Francesca , DAVIS, Paul Frank , ITINTEANG, Tinte , TAN, Swee Thong
- 申请人: Gillies Mcindoe Research Institute
- 申请人地址: Level 6 95 Custom House Quay Wellington NZ
- 专利权人: Gillies Mcindoe Research Institute
- 当前专利权人: Gillies Mcindoe Research Institute
- 当前专利权人地址: Level 6 95 Custom House Quay Wellington NZ
- 代理机构: Lewis, Graham Matthew
- 优先权: US201462036583P 20140812
- 国际公布: WO2016024870 20160218
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61K31/138 ; A61P35/00 ; G01N33/574 ; A61B5/00
摘要:
The present invention provides a novel approach to cancer diagnosis and therapy of cancer by providing compositions and methods for the identification and specific targeting of the cancer stem cell populations present in a tumour to eradicate, or slow or prevent tumour (5) growth and spread, including the potential for tumour metastasis, by modulation of the Renin-Angiotensin System including, but not limited to, Renin Receptor, Angiotensin II Receptor (2) and a secreted form of the Renin Receptor.
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