发明公开
EP3184521A1 INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF
审中-公开
INDAZOLE化合物作为FGFR激酶抑制剂，制备和使用
- 专利标题： INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF
- 专利标题（中）： INDAZOLE化合物作为FGFR激酶抑制剂，制备和使用
-
申请号： EP15833329.4申请日： 2015-08-19
-
公开(公告)号： EP3184521A1公开(公告)日： 2017-06-28
- 发明人: GENG, Meiyu , LIU, Lei , JIANG, Lei , HUANG, Min , ZHA, Chuantao , AI, Jing , WANG, Lei , CAO, Jianhua , DING, Jian
- 申请人： Shanghai Haihe Pharmaceutical Co., Ltd. , Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 申请人地址： 421 Newton Road Zhangjiang Hi-tech Park Pudong New Area Shanghai 201203 CN
- 专利权人： Shanghai Haihe Pharmaceutical Co., Ltd.,Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 当前专利权人： Shanghai Haihe Pharmaceutical Co., Ltd.,Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 当前专利权人地址： 421 Newton Road Zhangjiang Hi-tech Park Pudong New Area Shanghai 201203 CN
- 代理机构： Lenthall, Joseph
- 优先权： CN201410409467 20140819; CN201510073179 20150211
- 国际公布： WO2016026445 20160225
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D405/14 ; C07D231/56 ; C07D401/12 ; C07D471/04 ; C07D487/04 ; C07D401/14 ; C07D417/12 ; A61K31/496 ; A61K31/416 ; A61P35/00
摘要：
The present invention provides an indazole compound as a FGFR kinase inhibitor, preparation and use thereof. Specifically, the present invention provides a compound represented by formula (I), wherein the definitions of each group are described in the specification. The compound of the present invention has good FGFR kinase-inhibiting activity, and can be used in preparing a series of medicines for treating FGFR kinase activity related diseases.
公开/授权文献
信息查询
