发明公开
EP3194595A1 VIRAL RNA SEGMENTS AS IMMUNOMODULATORY AGENTS AND VACCINE COMPONENTS
审中-公开
作为免疫调节剂和疫苗组分的病毒RNA片段
- 专利标题： VIRAL RNA SEGMENTS AS IMMUNOMODULATORY AGENTS AND VACCINE COMPONENTS
- 专利标题（中）： 作为免疫调节剂和疫苗组分的病毒RNA片段
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申请号： EP15842717.9申请日： 2015-09-09
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公开(公告)号： EP3194595A1公开(公告)日： 2017-07-26
- 发明人: STAPLETON, Jack, T. , BHATTARAI, Nirjal , MCLINDEN, James , XIANG, Jinhau , DAVIDSON, Bev
- 申请人： University of Iowa Research Foundation
- 申请人地址： 112 N. Capitol Street 6 Gilmore Hall Iowa City, Iowa 52242-5500 US
- 专利权人： University of Iowa Research Foundation
- 当前专利权人： University of Iowa Research Foundation
- 当前专利权人地址： 112 N. Capitol Street 6 Gilmore Hall Iowa City, Iowa 52242-5500 US
- 代理机构： Rückerl, Florian
- 优先权： US201462051727P 20140917
- 国际公布： WO2016044023 20160324
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C12N15/00 ; C07K14/005 ; C07K14/18 ; A61K39/29 ; A61K39/12
摘要：
The disclosure provides compositions and methods involving viral RNA segments for use in modulating immune responses, including inhibition inflammation related to pathogenic T-cell activation. In addition, modification of the viral sequences responsible for modulating immune response provides for improved vaccine formulations.
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