- 专利标题： METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE
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申请号： EP15841682申请日： 2015-09-17
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公开(公告)号： EP3196193A4公开(公告)日： 2018-02-21
- 发明人: UEDA TSUYOSHI , UKAI KAZUTOSHI
- 申请人： DAIICHI SANKYO CO LTD
- 专利权人： DAIICHI SANKYO CO LTD
- 当前专利权人： DAIICHI SANKYO CO LTD
- 优先权： JP2014189572 2014-09-18
- 主分类号： C07D233/64
- IPC分类号： C07D233/64 ; A61K31/417 ; A61P43/00 ; C07B61/00
摘要：
A method for producing a compound (3), which comprises allowing a compound (1) to react with hydrogen gas in an inert solvent, in the presence of a specific chiral ligand and a ruthenium catalyst, or in the presence of an asymmetric transition metal complex catalyst previously generated from the chiral ligand and the ruthenium catalyst.
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