- 专利标题： OPTICALLY ACTIVE -TRIFLUORMETHYL- -AMINO ACID DERIVATIVE PRODUCTION METHOD
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申请号： EP15844955申请日： 2015-09-18
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公开(公告)号： EP3199524A4公开(公告)日： 2018-03-07
- 发明人: SHIBASAKI MASAKATSU , KUMAGAI NAOYA , YIN LIANG
- 申请人： MICROBIAL CHEMISTRY RES FOUNDATION
- 专利权人： MICROBIAL CHEMISTRY RES FOUNDATION
- 当前专利权人： MICROBIAL CHEMISTRY RES FOUNDATION
- 优先权： JP2014193476 2014-09-24
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D213/75
摘要：
A method for producing an optically active ±-trifluoromethyl-²-amino acid derivative, the method including: allowing a compound represented by the following General Formula (1) and a compound represented by the following General Formula (2) to react in the presence of a copper-optically active phosphine complex obtained from a copper compound and an optically active phosphine compound, to thereby obtain an optically active ±-trifluoromethyl-²-amino acid derivative represented by the following General Formula (3):
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