- 专利标题： METHOD OF PURIFYING IDRAPARINUX SODIUM
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申请号： EP15846879申请日： 2015-09-30
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公开(公告)号： EP3201210A4公开(公告)日： 2018-06-20
- 发明人: MENG JUNDONG , XU YONGGANG , WANG WENCUN , CHEN SONG , ZHANG HAONING
- 申请人： AMPHASTAR NANJING PHARMACEUTICALS INC
- 专利权人： AMPHASTAR NANJING PHARMACEUTICALS INC
- 当前专利权人： AMPHASTAR NANJING PHARMACEUTICALS INC
- 优先权： US201462059793 2014-10-03; US201514714191 2015-05-15
- 主分类号： C07H15/04
- IPC分类号： C07H15/04 ; C07H15/14
摘要：
A method for the purification of idraparinux sodium includes: passing a solution including a crude idraparinux sodium through a column including a sodium ion exchange resin to obtain a first mixture; passing a solution including the first mixture through a gel chromatogaphy column to obtain a second mixture; and precipitating a purified idraparinux sodium from a solution including the second mixture.
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