- 专利标题: FLUORINATED BENZOFURANYL-PYRIMIDINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP
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申请号: EP15778981.9申请日: 2015-10-14
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公开(公告)号: EP3207038B1公开(公告)日: 2018-08-22
- 发明人: KOSEMUND, Dirk , LÜCKING, Ulrich , SIEMEISTER, Gerhard , SCHOLZ, Arne , LIENAU, Philip
- 申请人: Bayer Pharma Aktiengesellschaft
- 申请人地址: Müllerstrasse 178 13353 Berlin DE
- 专利权人: Bayer Pharma Aktiengesellschaft
- 当前专利权人: Bayer Pharma Aktiengesellschaft
- 当前专利权人地址: Müllerstrasse 178 13353 Berlin DE
- 代理机构: BIP Patents
- 优先权: EP14189235 20141016
- 国际公布: WO2016059086 20160421
- 主分类号: C07D405/04
- IPC分类号: C07D405/04 ; A61K31/506 ; A61P35/00
摘要:
The present invention relates to fluorinated benzofuranyl-pyrimidine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper- proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
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