发明公开
- 专利标题： SUBSTITUTED TETRAHYDROPYRANS AND METHOD OF USE
- 专利标题（中）： 取代的四氢吡喃及其使用方法
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申请号： EP15854248.0申请日： 2015-10-29
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公开(公告)号： EP3212184A1公开(公告)日： 2017-09-06
- 发明人: KYM, Philip R. , WANG, Xueqing , SEARLE, Xenia B. , LIU, Bo , YEUNG, Ming C.
- 申请人： Abbvie S.a.r.l. , Galapagos NV
- 申请人地址： 26 Boulevard Royal Luxembourg LU
- 专利权人： Abbvie S.a.r.l.,Galapagos NV
- 当前专利权人： Abbvie S.a.r.l.,Galapagos NV
- 当前专利权人地址： 26 Boulevard Royal Luxembourg LU
- 代理机构： J A Kemp
- 优先权： US201462073586P 20141031
- 国际公布： WO2016069891 20160506
- 主分类号： A61K31/36
- IPC分类号： A61K31/36 ; A61K31/351 ; A61P11/00
摘要：
Compounds of formula (I) and pharmaceutically acceptable salts or radiolabelled forms thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and m are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
公开/授权文献
- EP3212184B1 SUBSTITUTED BENZOTETRAHYDROPYRANS AND THEIR USE 公开/授权日：2020-04-01
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