发明公开
EP3212648A1 TETRAHYDROPYRAZOLOPYRIDINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS
审中-公开
作为GHRELIN受体激动剂的四氢吡唑并吡啶衍生物
- 专利标题： TETRAHYDROPYRAZOLOPYRIDINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS
- 专利标题（中）： 作为GHRELIN受体激动剂的四氢吡唑并吡啶衍生物
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申请号： EP15854840.4申请日： 2015-11-02
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公开(公告)号： EP3212648A1公开(公告)日： 2017-09-06
- 发明人: IWATA, Yasuhiro , KAWAMURA, Kiyoshi , SUDO, Masaki , SHIMADA, Kaoru , KOIZUMI, Shinichi , TAKAHASHI, Nobuyuki , OBATA, Keiko , KURODA, Makiko
- 申请人： RaQualia Pharma Inc.
- 申请人地址： 1-21-19, Meieki Minami Nakamura-ku Nagoya-shi Aichi 450-0003 JP
- 专利权人： RaQualia Pharma Inc.
- 当前专利权人： RaQualia Pharma Inc.
- 当前专利权人地址： 1-21-19, Meieki Minami Nakamura-ku Nagoya-shi Aichi 450-0003 JP
- 代理机构： Witte, Weller & Partner Patentanwälte mbB
- 优先权： US201462073836P 20141031
- 国际公布： WO2016067638 20160506
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/43 ; A61P1/14 ; A61P3/08 ; A61P9/00 ; A61P11/00 ; A61P25/16 ; A61P29/00 ; A61P43/00
摘要：
The present invention relates to novel compounds of a formula (I) or a pharmaceutically acceptable salt or solvate thereof, processes for their preparation, pharmaceutical compositions comprising them and their use in therapy, for example as modulators of the growth hormone secretagogue receptor (also referred to as the ghrelin receptor or GHSR-1a receptor) and/or for the treatment and/or prophylaxis of a disorder mediated by the ghrelin receptor.
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