发明公开
EP3228315A1 PREVENTION OF ADVERSE EFFECTS CAUSED BY CD3 SPECIFIC BINDING DOMAINS
审中-公开
预防由CD3特异性结合域引起的不良影响
- 专利标题: PREVENTION OF ADVERSE EFFECTS CAUSED BY CD3 SPECIFIC BINDING DOMAINS
- 专利标题(中): 预防由CD3特异性结合域引起的不良影响
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申请号: EP17159560.6申请日: 2011-10-27
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公开(公告)号: EP3228315A1公开(公告)日: 2017-10-11
- 发明人: ZUGMAIER, Gerhard , NAGORSEN, Dirk , SCHEELE, Juergen
- 申请人: Amgen Research (Munich) GmbH
- 申请人地址: Staffelseestrasse 2 81477 München DE
- 专利权人: Amgen Research (Munich) GmbH
- 当前专利权人: Amgen Research (Munich) GmbH
- 当前专利权人地址: Staffelseestrasse 2 81477 München DE
- 代理机构: Schiweck, Weinzierl & Koch Patentanwälte Partnerschaft mbB
- 优先权: US412229P 20101110
- 主分类号: A61K31/573
- IPC分类号: A61K31/573 ; A61K39/395 ; C07K16/28
摘要:
The present invention relates to a glucocorticoid (GC) for use in the amelioration, treatment or prophylaxis of neurological/psychiatric adverse events caused by a CD3 binding domain. Kits comprising a GC, a CD3 binding domain and instructions for use which indicate that the GC is to be employed for the treatment amelioration and/or prophylaxis of neurological adverse events caused by said CD3 binding domain, are also disclosed.
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