发明公开
- 专利标题: AQUEOUS DENTAL GLASS IONOMER COMPOSITION
- 专利标题(中): 水性牙科玻璃离聚体组合物
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申请号: EP16169725.5申请日: 2016-05-13
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公开(公告)号: EP3231412A3公开(公告)日: 2017-10-25
- 发明人: RENN, Caroline , ELSNER, Oliver , MAIER, Maximilian , SZILLAT, Florian , KLEE, Joachim E. , WEBER, Christoph , WALZ, Uwe , SCHEUFLER, Christian , RITTER, Helmut , LICHKUS, Andrew Murray , JIN, Xiaoming
- 申请人: DENTSPLY DETREY GmbH , Dentsply Sirona Inc.
- 申请人地址: De-Trey-Strasse 1 78467 Konstanz DE
- 专利权人: DENTSPLY DETREY GmbH,Dentsply Sirona Inc.
- 当前专利权人: DENTSPLY DETREY GmbH,Dentsply Sirona Inc.
- 当前专利权人地址: De-Trey-Strasse 1 78467 Konstanz DE
- 代理机构: Hartz, Nikolai
- 优先权: US201662322983P 20160415
- 主分类号: A61K6/083
- IPC分类号: A61K6/083
摘要:
The present invention relates to an aqueous dental glass ionomer composition comprising
(A) a reactive particulate glass,
(B) a water-soluble, polymerizable polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the polymerizable polymer has a polymer backbone and pendant groups having one or more polymerizable carbon-carbon double bonds, wherein the polymerizable polymer is obtainable by a process comprising
a) a step of polymerizing a mixture comprising
(i) a first polymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and optionally
(ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary hydroxyl and/or amino group(s) and a second polymerizable organic moiety, for obtaining an water-soluble polymer;
b) a step of coupling to the water-soluble polymer a compound having a polymerizable moiety and a functional group reactive with an optionally protected carboxylic acid group of repeating units derived from the first polymerizable monomer or an optionally protected hydroxyl and/or amino group of repeating units derived from the second copolymerizable monomer in the water-soluble polymer obtained in step a), wherein the optionally protected carboxylic acid group and the optionally protected hydroxyl and/or amine group are deprotected, so that polymerizable pendant groups are linked to the backbone by ester groups, urethane groups and/or amide groups,
and, optionally, a step of deprotecting the protected carboxylic acid group after step a) or step b), for obtaining a polymerizable polymer;
(C) a hydrolysis-stable, water-soluble monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; and
(D) a polymerization initiator system.
(A) a reactive particulate glass,
(B) a water-soluble, polymerizable polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the polymerizable polymer has a polymer backbone and pendant groups having one or more polymerizable carbon-carbon double bonds, wherein the polymerizable polymer is obtainable by a process comprising
a) a step of polymerizing a mixture comprising
(i) a first polymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and optionally
(ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary hydroxyl and/or amino group(s) and a second polymerizable organic moiety, for obtaining an water-soluble polymer;
b) a step of coupling to the water-soluble polymer a compound having a polymerizable moiety and a functional group reactive with an optionally protected carboxylic acid group of repeating units derived from the first polymerizable monomer or an optionally protected hydroxyl and/or amino group of repeating units derived from the second copolymerizable monomer in the water-soluble polymer obtained in step a), wherein the optionally protected carboxylic acid group and the optionally protected hydroxyl and/or amine group are deprotected, so that polymerizable pendant groups are linked to the backbone by ester groups, urethane groups and/or amide groups,
and, optionally, a step of deprotecting the protected carboxylic acid group after step a) or step b), for obtaining a polymerizable polymer;
(C) a hydrolysis-stable, water-soluble monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; and
(D) a polymerization initiator system.
公开/授权文献
- EP3231412A2 AQUEOUS DENTAL GLASS IONOMER COMPOSITION 公开/授权日:2017-10-18
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